Effects of Dietary Freeze-dried Strawberries on Plasma Trace Elements and Antioxidants in Adults with Obesity and above Optimal Serum Lipids
Abstract
Dietary flavonoid intake, especially berry flavonoids, has been associated with antioxidant functions and metal chelation in mechanistic studies. We examined the hypothesis that freeze-dried strawberries (FDS) improve antioxidant biomarkers in adults with abdominal adiposity and elevated serum lipids. In a randomized dose-response controlled trial, 60 volunteers [5 men and 55 women; age: 49 � 10 years; BMI: 36 � 5 kg/m2 (mean�SD)] were assigned to one of the following arms: low dose FDS (LD-FDS) (25g/d), low dose control (LD-C), high dose FDS (HD-FDS) (50g/d), and high dose control (HD-C) beverages for 12 weeks. Control beverages were matched for calories and total fiber. Serum levels of trace elements and whole blood glutathione, and catalase activity were examined at screening (0 week) and after 12 weeks intervention. At 12 weeks, glutathione levels were higher in HD-FDS vs. LD-FDS, as well as vs. HD-C, and catalase activity was lower in HD-FDS vs. baseline (all P<0.05). No differences were noted in serum trace elements following FDS intervention. Thus, dietary strawberries may selectively modulate antioxidant biomarkers that influence risk factors of chronic diseases.
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- OSU Theses [15752]