Mannheimia Haemolytica Chimeric Outer Membrane Protein Plpe and Leukotoxin Epitopes as a Vaccine or Vaccine Component Against Shipping Fever
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Date
2010-09-14Author
Ayalew, Sahlu
Confer, Anthony W.
Board of Regents/Oklahoma State University and the A & M Colleges
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Vaccine preparations for the prevention and treatment of bovine respiratory disease (BRD) and, in particular, its most severe form, termed "shipping fever", are provided. The preparations comprise chimeric proteins comprising immunodominant epitopes of recombinant Mannheimia haemolytica outer membrane protein PlpE, and immunodominant epitopes of recombinant M. haemolytica leukotoxin.
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