Now showing items 1-1 of 1

    • HSP90 C-terminal Domain Binding Site For Novobiocin and Related Coumarins 

      Szabla, Kristen Lynn (Oklahoma State University, 2010-05-01)
      Heat shock protein 90 (Hsp90) is a highly conserved, eukaryotic, molecular chaperone which stabilizes an assortment of oncogenic proteins. Currently, novobiocin and related coumarins are being developed into higher affinity ...