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    • Crystallization of interleukin-18 for structure-based inhibitor design 

      Krumm, Brian; Meng, Xiangzhi; Xiang, Yan; Deng, Junpeng (International Union of Crystallography, 2015)
      Interleukin-18 (IL-18) is a pleiotropic pro-inflammatory cytokine belonging to the IL-1 superfamily. IL-18 plays an important role in host innate and acquired immune defense, with its activity being modulated in vivo by ...