Browsing by Author "Lloyd, Pamela G."
Now showing items 1-7 of 7
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Effects of dynamic shear stress on endothelial cells, platelets and their interactions
Shanmugavelayudam, Saravan Kumar (2013-05)Coronary heart disease (CHD), characterized by degenerative changes in coronary circulation, is the leading cause of death in the US. Vascular wall endothelial cells (EC) and circulating blood platelets play a major role ... -
Effects of Physiologically Relevant Shear Stress and Platelet-endothelial Cell Interaction on Platelet Activation and Platelet Microparticle Generation
Rouf, Farzana (Oklahoma State University, 2011-05-01)The major scope of this study was to investigate the effects of physiologically relevant shear stresses and platelet-endothelial cell (EC) interactions on platelet activation, and platelet microparticle (PMP) generation. ... -
Mechanisms of equine insulin resistance
Banse, Heidi Elise (2013-05)Equine metabolic syndrome, a condition characterized by obesity, insulin resistance (IR) or hyperinsulinemia, and laminitis is a common endocrine disorder of horses. The mechanisms responsible for the development of equine ... -
Novel Mechanisms Underlying Diabetes-Induced Atrial Fibrillation
Maria, Zahra (2016-07-01)Diabetes results from a defect in insulin production (type-1) or action (type-2) causing dysfunctional glucose uptake. Diabetic patients are predisposed to cardiac complications such as atrial fibrillation (AF). The heart ... -
Regulation of placental growth factor by fluid shear stress in the vessel wall
Rashdan, Nabil Aiman (2015-07)Arteriogenesis is the process by which mature arteries form from collateral arterioles after upstream arterial stenosis or occlusion. During collateral remodeling, monocytes are recruited to the vessel wall. Placental ... -
Responses of vascular cells to shear stress and diabetes-associated metabolic dysfunction
Rouf, Farzana (2016-12)Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for 30% of all deaths. Coronary artery disease (CAD - narrowing of arteries), most common type of CVD, results in altered shear stress that ... -
Role of MicroRNAs in Lung-Associated Diseases
Zhang, Li (2015-05-01)MicroRNAs (miRNAs) are small non-coding RNAs that can repress protein synthesis by translational repression and mRNA decay to regulate signaling pathways. miRNAs play important roles in various cellular processes including ...