Farrell, John W.Bemben, Debra A.Black, Christopher D.Larson, Daniel J.Pardo, GabrielFjeldstad-Pardo, CecilieLarson, Rebecca D.2019-11-052019-11-052019-09-17Farrell, J. W., Bemben, D. A., Black, C. D., Larson, D. J., Pardo, G., Fjeldstad-Pardo, C., & Larson, R. D. (2019). Evaluation of Power Production Asymmetry during Cycling in Persons with Multiple Sclerosis. International Journal of Environmental Research and Public Health, 16(18), 3445. doi: 10.3390/ijerph16183445https://hdl.handle.net/11244/321767Lower limb asymmetries have been observed in persons with multiple sclerosis (PwMS), and have been associated with mobility impairment. An incremental cycling test was performed on a cycle ergometer to determine peak power output (PPO) and peak oxygen consumption (VO2peak). Then, participants cycled at 50%, 60%, and 70% of their PPO to assess the contribution of each lower limb to power production. Two-way repeated measures ANOVA was used to detect group × intensity differences in power production asymmetry. Eight PwMS and six healthy individuals (Non-MS) completed the study. No statistically significant (p > 0.05) group × intensity interactions or main effects were present when examining between-limb differences in power production. The current data do not indicate a statistically significant difference in power production asymmetry between groups and exercise intensities. Previous research has established a 10% difference between contralateral limbs as a threshold for asymmetry. The average asymmetry in power production in PwMS exceeded the 10% threshold at all measured outputs, suggesting the presence of asymmetry in power production.Attribution 4.0 Internationalmultiple sclerosisasymmetryexerciselower extremitywalkingArticle10.3390/ijerph16183445