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Comparison of adverse event reporting between adolescent and young adults and older adults with cancer enrolled in Phase II/III clinical trials
(Oklahoma State University Center for Health Sciences, 2023-02-17)
Background: Momentum to improve cancer outcomes in adolescents and young adults (AYAs, diagnosed between 15-39 years of age) has been growing in recent years. However, there remains to be significant barriers to understanding ...
Influence of COVID-19 on contraception: a cross-sectional analysis of disrupted clinical trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: The COVID-19 pandemic exacerbated barriers to contraceptive services and disrupted the progression of ongoing clinical trials (CTs) in several fields of medicine1–4, including contraceptive care. Further, ...
Pediatric autoimmune clinical trial discontinuation and non-publication: An analysis of the National Library of Medicine
(Oklahoma State University Center for Health Sciences, 2023-02-17)
Background: With the rise in pediatric autoimmune diseases in the United States, it is both clinically relevant and timely to analyze the safety, cost-effectiveness, and efficacy of treatment options. The methodical research ...
COVID 19 and its effects on pediatric orthopaedic clinical trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Clinical trials for the treatment of pediatric orthopaedics are critical to enhance the quality of life of these children. In response to the COVID-19 pandemic, the FDA updated guidance on conducting clinical ...